Summary: Hematopoiesis is particularly sensitive to DNA damage.Myeloid tumor incidence increases in patients with DNA repair defects and after chemotherapy.It is not known why hematopoietic cells are highly vulnerable to DNA damage.Addressing this question is complicated by the paucity of mouse models of hematopoietic malignancies due to defective
Design and Analysis of Double-Gate MOSFETs for Ultra-Low Power Radio Frequency Identification (RFID): Device and Circuit Co-Design
Recently, double-gate MOSFETs (DGMOSFETs) have been shown iphone 14 price winnipeg to be more optimal for ultra-low power circuit design due to the improved subthreshold slope and the reduced leakage current compared to bulk CMOS.However, DGMOSFETs for subthreshold circuit design have not been much explored in comparison to those for strong inversi
K13-Mediated Reduced Susceptibility to Artemisinin in Plasmodium falciparum Is Overlaid on a Trait of Enhanced DNA Damage Repair
Summary: Southeast Asia has been the hotbed for the development of drug-resistant malaria parasites, including those with resistance to artemisinin combination therapy.While mutations in the kelch propeller domain (K13 mutations) are associated with artemisinin resistance, a range of evidence suggests that other factors are critical for the establi
The geomorphic structure of the runoff peak
This paper develops a theoretical framework to investigate the core dependence of peak flows on the geomorphic properties of river basins.Based on the theory of transport by travel times, and simple hydrodynamic characterization of floods, this new framework invokes the linearity and invariance of the hydrologic response to provide analytical and s
LC/DC: Lockless Containers and Data Concurrency a Novel Nonblocking Container Library for Multicore Applications
Exploiting the parallelism in multiprocessor systems is a major challenge in modern computer science.Multicore programming demands a change in the way we design and use fundamental data structures.The standard collection of data structures and algorithms in C++11 is the sequential standard template library (STL).In this paper, we present their visi